Effect Of Some Natural Products Isolated From Polygonum Persicaria Roots On The Growth Of Salmonella Enterica Typhimurium And Staphylococcus Aureus.

Abstract

The current study included the separation and identification of several active compounds
that found in Polygonum persicaria through a separation process by using a sequence of
solvents system extraction that included three solvents of different polarities: petroleum ether
(60-80 0C), ethanol, and hot aqueous extract. The phenolic compounds were identified by
using high-performance liquid chromatography HPLC, and seven of the phenolic compounds
were identified (Quercetin, Catechine, Caffeic acid, Rutin, Kaempferol, Gallic acid and
Myricetin).
Biologically, the results showed that the ethanolic extract of the seeds had an inhibitory effect
on the bacteria under study. As the effect of inhibition was at a concentration of (200 mg/ml)
with a diameter of (6 , 11) mm on S. aureus and S. enterica Typhimurium, respectively, and
there was a significant difference between the concentrations, and at the two concentrations
(100, 50 mg/ml) the inhibitory effect of both types was on S. aureus and S. enterica
Typhimurium with the same amount (4, 8) mm, respectively, with no significant differences.
The inhibitory effect of the hot water extract of the seeds was low compared to the ethanolic
extract, at a concentration of (200, and 100 mg / ml), and the effect of inhibition on S. aureus
was (6,4) mm, respectively.